Fig. 1: Construction of the prognostic risk model for CRC patients.
From: RNF4 mediated degradation of PDHA1 promotes colorectal cancer metabolism and metastasis
A Volcano plot of prognostic-related proteins obtained from univariate COX analysis. Red dots represent high-risk proteins; blue dots represent low-risk proteins; B LASSO regression analysis curve, with different colored curves representing different proteins; C Cross-validation error curve of LASSO regression. The x-axis represents the log(λ) value and the y-axis represents the Partial Likelihood Deviance. The number of proteins retained for each log(λ) value used for calculation is shown above the graph with a dashed line indicating the log(λ) value and the number of genes retained when the Partial Likelihood Deviance is optimal; Kaplan–Meier curves analyzing the relationship between risk scores of the prognostic risk model and OS in the all (D), train (E), and test (F) datasets of CRC patients. n = 336 (excluding samples with unknown survival status and survival time of 0).
