Fig. 5: Identification of critical TF for YTHDC2 in macrophages. | npj Precision Oncology

Fig. 5: Identification of critical TF for YTHDC2 in macrophages.

From: YTHDC2 manipulates anti-tumoral macrophage polarization and predicts favorable outcomes in triple negative breast cancer

Fig. 5

a Identification of TFs for YTHDC2-high/YTHDC2-low macrophages. Blue boxes highlight the TFs associated with YTHDC2-high macrophages. Red color indicates the TFs that regulate the largest number of genes. Brackets indicate the number of genes regulated by each TF. b Interaction network of the six critical TFs upregulated by YTHDC2 in macrophage. c Overlap between genes related to YTHDC2 and genes related to ATF3 in the GeneCards database.

Back to article page