Fig. 8: Level of KIF11 protein expression in filanesib or vehicle treated murine tissues. | npj Precision Oncology

Fig. 8: Level of KIF11 protein expression in filanesib or vehicle treated murine tissues.

From: Functional screening identifies kinesin spindle protein inhibitor filanesib as a potential treatment option for hepatoblastoma

Fig. 8

KIF11 expression in HB PDX FFPE tissue samples was evaluated by immunohistochemistry. Baseline KIF11 expression was high in all samples (A–E). A decrease in KIF11 expression after filanesib treatment was evident in 2/5 HB PDX tumors, HB-279 (B) and HB-284 (D). H&E-staining shows the histology of the tumors (A–E). Scale bar = 50 μm. Close-ups in the corners: scale bar = 50 μm.

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