Table 1 Baseline patient characteristics (n = 20)

From: Neoadjuvant chemoradiotherapy plus sintilimab in pMMR/MSS rectal cancer patients with PD-L1 TPS ≥ 1% or CPS ≥ 1: an open-label, prospective, phase II study

Characteristic

n (%)

Age, median (IQR)

56.5 (47.5–66.0)

Sex

 Male

16 (80.0)

 Female

4 (20.0)

ECOG performance status

 1

1 (5.0)

 0

19 (95.0)

Clinical tumor stage

 T2

2 (10.0)

 T3

13 (65.0)

 T4a

5 (25.0)

Clinical nodal stage

 N0

6 (30.0)

 N+

14 (70.0)

Extramural vascular invasion

 Positive

9 (45.0)

 Negative

11 (55.0)

Mesorectal fascia

 Positive

6 (30.0)

 Negative

14 (70.0)

Distance from primary tumor to anal verge (cm)

 <5

12 (60.0)

 5–10

8 (40.0)

PD-L1 expression, TPS

 ≥1%

3 (15.0)

 <1%

17 (85.0)

PD-L1 expression, CPS

 ≥1%

20 (0.0)

 <1%

0 (0.0)

Baseline CEA level

 Normal (<5 ng/mL)

10 (50.0)

 Abnormal (≥5 ng/mL)

10 (50.0)

  1. Data are median (IQR) or n (%)
  2. ECOG Eastern Cooperative Oncology Group, TPS tumor cell proportion score, CPS combined positive score, CEA, carcinoembryonic antigen