Fig. 4: Testing a cancer prediction model that uses cancer-associated RFUs.
From: Circulating T-cell receptor repertoire for cancer early detection
(a) Volcano plot of RFU-cancer associations. The boxplots on either side of the volcano plot show covariate-adjusted RFU TCR counts of a positively and a negatively cancer-associated RFU, as indicated by the dashed arrows. (b) ROC curves for train and test folds from 10-fold cross-validation, broken down by cancer stage. (c) Stage I cancer sensitivity based on cross-validated test fold cancer scores as shown in (b). (d) Comparison of cross-validated cancer prediction scores by cancer stage or benign lung nodule status.
