Fig. 6: Sexually dimorphic profiles of LINE-1, p53, and RB in human lung adenocarcinomas overexpressing HDM2.
From: LINE1 insertion into the NACC2 locus disrupts the HDM2 axis and activates lung oncogenic signaling
a IHC profiles of LINE-1 and HDM2 proteins, and b p53 and RB in male and female lung tumors overexpressing HDM2. Scale bars = 20 μm. c–f Quantification of IHC signals in multiple sections of human lung tumor samples. IHC N = 5 males and 5 females.
