Fig. 9: Experiments in breast cancer cell lines after PTGDS overexpression.
From: Pan cancer research reveals the role of PTGDS in tumor suppression and immune regulation
a, b Colony formation assays. After PTGDS overexpression, the proliferation ability of breast cancer cell lines MDA-MB-231 and HCC1806 is significantly decreased. c, d Wound healing assays. After PTGDS overexpression, the migration ability of breast cancer cell lines MDA-MB-231 and HCC1806 is significantly decreased. e, f Transwell assays. After PTGDS overexpression, the migration and invasion abilities of breast cancer cell lines MDA-MB-231 and HCC1806 are significantly reduced. g, h Multiple immunohistochemical staining was performed to verify the co-localization of PTGDS CD8+ T cells and CD20+ B cells in clinical samples. (Z-score test: *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.).
