Table 3 Overview of the 19 publications with the goal of predicting current or future neuromotor outcomes for infants
Author | Year | Setting | Sample size | Data collection age | Outcome OR ground truth | Technology | Goal | Best Prediction Result | |
---|---|---|---|---|---|---|---|---|---|
Cerebral palsy | |||||||||
1 | Adde76 | 2010 | Clinic | 30 | 10–15 weeks CA | CP at 4–7 years; GMA at 10–15 weeks CA | Video | Predict - Future | CP Prediction: AUC-ROC = 0.88, Sn = 0.85, Sp = 0.88 |
2 | Stahl77 | 2012 | Clinic | 82 | 10–18 weeks CA | CP at 2–5 years | Video | Predict - Future | CP Prediction: Sn = 0.85, Sp = 0.96, Acc = 0.94 |
2 | Adde45 | 2013 | Clinic | 52 | 9–17 weeks CA | CP at 2 years; GMA at 9–14 weeks CA | Video | Automate, Predict - Future | CP Prediction: AUC-ROC = 0.85, Sn = 0.89, Sp = 0.74 |
3 | Rahmati78 | 2014 | Lab | 78 | 10–18 weeks CA | CP at 5 years | Video | Predict - Future | CP Prediction: Sn = 0.50, Sp = 0.95, Acc = 0.87 |
4 | Rahmati42 | 2016 | Lab | 78 | 10–18 weeks CA | Unclear diagnosis of CP | Sensor; Video | Predict - Future | Using video: CP Prediction: Sn = 0.86, Sp = 0.92, Acc = 0.91, AUC-ROC = 0.93 |
5 | Orlandi47 | 2018 | Clinic | 173 | 3–5 months CA | Bayley III at 18–24 months for motor impairment or CP diagnosis; GMA at 3–5 months CA | Video | Automate, Predict - Future | CP Prediction: Acc = 0.92, Sn = 0.44, Sp = 0.99, AUC = 0.82 |
6 | Raghuram79 | 2019 | Clinic | 152 | 3.81 ± 0.4 months CA | Bayley-III at 18–24 months for CP diagnosis | Video | Predict - Future | CP Prediction: Acc = 0.66, Sn = 0.79, Sp = 0.63, PPV = 0.37, NPV = 0.91 |
7 | Ihlen80 | 2019 | Clinic | 377 | 12 weeks CA | CP at 18 months - 5 years | Video | Predict - Future | CP Prediction: Sn = 0.93, Sp = 0.82, PPV = 0.38, NPV = 0.99, AUC-ROC = 0.87 |
8 | Moro81 | 2022 | Lab | 142 | 40 weeks PMA | Bayley-III at 30 months | Video | Predict - Future | CP Prediction: Acc = 0.86 |
9 | Raghuram82 | 2022 | Clinic | 252 | 3–5 months CA | CP diagnosis at 18–24 months | Video | Predict - Future | CP Prediction: Sn = 0.55, Sp = 0.80, PPV = 0.26, NPV = 0.93 |
10 | Groos83 | 2022 | Clinic | 557 | 11–13 weeks | CP diagnosis at 18 months - 5 years | Video | Predict - Future | CP Prediction: Sn = 0.71, Sp = 0.94, PPV = 0.68, NPV = 0.95, Acc = 0.91 |
ASD tendency | |||||||||
11 | Doi93 | 2022 | Lab | 41 | 4 months | M-CHAT for risk of ASD at 18 months | Video | Predict - Future | ASD Tendency Prediction: Sn = 0.71, Sp = 0.97, F1 = 0.77, AUC-ROC = 0.90, ROC-PR = 0.69 |
12 | Doi84 | 2023 | Clinic | 73 | 2.13 ± 0.66 days CA | M-CHAT at 18 months CA | Video | Predict - Future | ASD Tendency Prediction: Sn = 0.57; Sp = 0.97 |
Other neurodevelopmental delay/disorders | |||||||||
13 | Chambers85 | 2020 | Home; Clinic | 104 | 3–8 months CA | Bayley Infant Neurodevelopmental Screener | Video | Predict - Current | N/A |
14 | Tacchino70 | 2020 | Home; Clinic | 67 | 39–41 weeks PMA; 8–12 weeks after birth | MRI or GMA at 8–12 weeks after birth | Video | Illuminate, Predict - Current | Preterm Status Classification: Acc = 0.95 |
15 | Fitter43 | 2020 | Home | 36 | 1–20 months CA | Parent report at 24 month | Sensor | Predict - Current, Predict - Future | DD Risk Level Classification: Acc = 0.89, Pr = 0.95, Rc = 0.88, F1 = 0.91; DD Outcome Prediction: Acc = 0.90, Pr = 0.82, Rc = 1, F1 = 0.90 |
16 | Garello86 | 2021 | Lab | 55 | 40 weeks PMA | Bayley-III at 2 years | Video | Predict - Future | Neuromotor Disorders Prediction: Acc = 0.78, Sn = 0.79 Sp = 0.78 |
17 | Celik34 | 2023 | Clinic | 101 | TD: 14.1 ± 2.9 weeks CA; AR: 12.6 ± 3.2 weeks CA | GMA at 9–20 weeks CA | Sensor | Illuminate, Predict - Current | GMA score: Sn = 0.85; Sp = 0.83; Acc = 0.83 |
18 | de’Cavalieri44 | 2023 | Home | 17 | 6.35 ± 2.95 months CA | AIMS/IMP at 6.35 ± 2.95 months CA | Sensor | Predict – Future, Predict - Current | N/A |
19 | Taleb87 | 2023 | Home; Clinic | 21 | TD: 15.8 ± 14 weeks CA; Bronchiolitis: 13 ± 12.5 weeks CA; SMA: 80.8 ± 45.5 weeks CA | TD: 15.8 ± 14 weeks CA; Bronchiolitis: 13 ± 12.5 weeks CA; SMA: 80.8 ± 45.5 weeks CA | Video | Predict-Current | Neuromotor Disorders Prediction: Pr = 0.81; Rc = 0.86; Acc = 0.86; AUC-ROC = 0.72 |