Fig. 6: Treatment outcomes with and without optimization.
a–d shows the improvement in outcomes for the whole cohort (n = 105) with the first step of multi-step optimization, second step of multi-step optimization, simultaneous optimization, and midway optimization, respectively. In each panel, the light blue and light red violin plots depict the distribution of predicted outcomes with the actual schedule and the optimized schedule, respectively. The boxplots show the median (red line) and IQR (blue box) of the corresponding outcomes. All three optimization strategies lead to a significant reduction of TVT when compared to the treatment schedule the patient actually received.
