Table 1 Findings of the review
Citation | Objective | Study design | Intervention | Delivery Personnel | Setting | Length | Frequency | Theory | Patient demographics | Age range | Stage | Treatment phase |
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To explore VR as a distraction intervention to relieve symptom distress in adults receiving chemotherapy for breast, colon, and lung cancer | Crossover design where participants served as their control |
| Nurses | clinical based | Single session | A single session of VR during one chemotherapy treatment, with a control condition (no VR) for an alternate matched treatment, 45-90 minutes | Lazarus and Folkman’s stress and coping model | Adults with breast, colon, or lung cancer (33%), primarily female (77%), average age of 54, predominantly Caucasian (91%) | 32–78 | NA | Post-treatment | |
To assess the impact of the cancer care dialogues model (home telehealth program) on age-related differences in health-related quality of life (HRQOL) for cancer patients receiving chemotherapy | Prospective pilot study | Daily telehealth interactions with a care coordinator (registered nurse) to manage chemotherapy-related symptoms | nurses | home-based | 6 months | Daily symptom monitoring and weekly follow-up | NA | Veterans with a new cancer diagnosis and planning to undertake chemotherapy, predominantly male | Mean age 63.7 years (10.3) | local and metastatic | Active treatment | |
To develop and evaluate an online resource for stereotactic ablative radiotherapy (SABR) information for lung cancer patients using qualitative user feedback | Qualitative user testing with “think-aloud” and semi-structured interviews | A website designed to provide treatment information for early-stage lung cancer patients considering SABR | oncologists, psychologists | home-based | Single session | One-time user interaction with website | user-centered design principles | Lung cancer patients eligible for SABR, primarily older adults with varied health literacy, NSCLC | Average 64.4 Phase 2, 66.3 Phase 3 | local | Active treatment | |
Explore why patients and caregivers use online specialists for cancer questions. | Qualitative study with semi-structured telephone interviews. | Web-based Q&A portal on the DLIC website. | Physician | home-based | NA | Based on needs | NA | lung cancer patients (One patient had small cell lung cancer (SCLC), three had non-small cell lung cancer (NSCLC) | 44–62 | local and metastatic | Pre-treatment | |
To evaluate the efficacy of an internet-based intervention in improving the quality of life for patients with chronic post-surgical pain (CPSP) after lung cancer surgery | Retrospective cohort study comparing Internet-based intervention with conventional treatment | Internet-based pain management intervention, including remote pain control, lifestyle advice, and psychological support via smartphones and Internet | emergency department hcp | home-based | 3 months | Weekly assessments and guidance for the internet-based group | NA | Lung cancer patients with chronic post-surgery pain after thoracotomy or thoracoscopic surgery | average 61 years | NA | Active treatment | |
To assess if a web-mediated follow-up improves overall survival (OS) in advanced-stage lung cancer patients compared to routine follow-up with scheduled CT scans. | Multicenter phase III randomized controlled trial | Web-mediated follow-up using an e-follow-up application for weekly self-scored symptoms, triggering alerts for oncologists based on abnormal results | Physician | home-based | 13 months | Weekly symptom reporting via the mobile app; oncologist visits at least every three months for both groups | NA | NSCLC and SCLC | 35.7–88.1 | local and metastatic | Active treatment | |
To evaluate whether a Web-based symptom self-reporting tool could improve survival by enabling early detection of relapse in lung cancer patients | Retrospective, nonrandomized cohort study with an experimental arm using the “sentinel” Web app for symptom reporting and a control arm with standard follow-up | self-reported symptom assessment via the web application alerts an oncologist for early intervention based on predefined criteria | Physician | home-based | 18 months | Weekly | NA | Lung cancer patients with complete response, surgical excision, or detectable but nonprogressive disease | Median age of 63–64 years | local and metastatic | Post-treatment | |
To evaluate the feasibility, usability, and preliminary impact of MyAVL, an interactive patient portal for lung cancer patients | Feasibility study with mixed methods (questionnaires, focus group, log data analysis) | MyAVL portal provides patient education, appointment overview, EMR access, PROs with feedback, and tailored physical activity support | research team | home-based | 4 months | Patients accessed MyAVL as often as desired | NA | All white, 47% women, NCSLC patients | 40–76 | local and metastatic | Active treatment | |
To determine if an automated symptom management system (Symptom Care at Home, SCH) reduces chemotherapy-related symptoms compared to enhanced usual care (UC). | Longitudinal randomized controlled trial | Daily automated symptom reporting, self-management coaching, automated alert for poorly controlled symptoms, and nurse practitioner (NP) follow-up using a decision support system | nurses | home-based | 6 months | daily | NA | 358 participants, the majority female (75%), White (~80%), and a variety of cancer (lung cancer 17%) | Mean age of 55.77 years | local and metastatic | Active treatment | |
Tests new ways of working to identify unmet needs and support patients’ transition from acute to primary care on completion of treatment. | survey, questionnaire, cohort study | Patients complete eSPARC electronic questionnaires monthly, combined with telephone consultations. | Lung cancer nurse specialists | home-based | 6 months | Monthly assessments | NA | 20 NSCLC patients’ post-surgery, radiotherapy, or chemotherapy. | 50–80+ | NA | Active treatment | |
To assess the feasibility and acceptability of tablet-assisted self-reported symptom assessment for lung cancer symptoms | Mixed-method feasibility study | Tablet PC-assisted symptom assessment targeting dyspnea, fatigue, pain, and anxiety | nurses | clinical based | Single session | One-time assessment | NA | newly diagnosed lung cancer patients | 53–89 | NA | Active treatment | |
Determine the feasibility and efficacy of smartphone app-based PR on exercise capacity, symptom management, and QoL in patients with advanced lung cancer undergoing chemotherapy | prospective, single-arm intervention study | A comprehensive mobile health care app with a pulmonary rehabilitation program and symptom management resources, and an Internet of Things wearable device | Physician | home-based | 12 weeks | Daily | NA | 46.0% (46/100) were males. | median55.1 | local and metastatic | Post-treatment | |
Assess the feasibility of a telehealth physical activity intervention for older adults with cancer and their caregivers. | A pilot study with pre/post assessments of physical and functional outcomes. | Telehealth sessions with PT/OT to improve physical activity before and after surgery. | Physical and occupational therapists | are home-based | 5 sessions | Sessions held before surgery post-discharge (days 7, 14, and 2-4 weeks after surgery). | Chronic care self-management model | 34 patient/caregiver dyads (16 GI cancer, 18 lung cancer) | 68–83 | NA | Active treatment | |
Assess the feasibility of HRQoL assessment using ePRO in daily clinical practice. | Single-center prospective feasibility study. | Patients completed HRQoL questionnaires before each visit using tablets or computers. | Physicians, clinical research assistant | both | 4 months | before each visit | NA | breast, colorectal, and lung cancer patients receiving systemic therapies. Lung cancer (n = 50) | 54–71 | local and metastatic | Pre-treatment | |
To assess the impact of telemedicine on time to treatment initiation and accessibility of care for thoracic oncology patients during the COVID-19 pandemic | Retrospective cohort study | Telemedicine visits via phone or video conference | Physician | home-based | 3 months | As determined by patient needs and clinical protocol | NA | 240 patients with thoracic malignancies, majority NSCLC, SCLC | 60–75 | local and metastatic | Post-treatment | |
Evaluate Value-Based Healthcare (VBHC) principles with digital weekly follow-up for lung cancer patients. | Mixed method | Digital portal for patient-reported outcome monitoring and follow-up. | oncologists, nurses, dieticians | home-based | 30 months | Weekly digital assessments. | Value-Based Healthcare principles. | lung cancer patients (NSCLC and SCLC), 79% male | 34–90 | local and metastatic | Active treatment | |
To evaluate the feasibility, acceptability, and preliminary effectiveness of a videoconference-based physical activity (PA) program for reducing fatigue in cancer patients on immune checkpoint inhibitors | Single-arm feasibility study | Six-month videoconference-based PA program combining supervised and autonomous sessions targeting fatigue reduction | physiologists | home-based | 6 months | Weekly | NA | Of cancer patients experiencing fatigue while on immune checkpoint inhibitors, 18.75% of lung cancer patients | 34–72 | Advanced stage, metastatic | Post-treatment | |
To investigate the feasibility, acceptability, safety, and potential efficacy of inspiratory muscle training (IMT) and walking promotion to disrupt a postulated “dyspnea-inactivity” spiral. | A parallel group pilot randomized trial | 12-week intervention, delivered via telemedicine, consisted of exercise training (IMT + walking), education, and behavior change support. | trainer | home-based | 12 weeks | Tele-visits were scheduled for weeks 1, 3, 5, 7, 9, and 12 (bi, tri-weekly) | Social Cognitive Theory | lung cancer survivors from Kaiser Permanente Colorado who completed curative-intent therapy within 1–6 months | Control: 70.3 (7.4), Intervention 68.3(6.4) | local and metastatic | Active treatment | |
To evaluate the efficacy of a mHealth portal, Symptom Care at Home (SCH), in assisting caregivers in managing symptoms for patients in home hospice care. | Randomized controlled trial (RCT) | SCH automated symptom reporting system with caregiver coaching and nurse notifications based on the severity of symptoms | nurses | home-based | Ongoing | daily | NA | Cancer patients in home hospice care, predominantly non-hispanic white, lung cancer 19% | Median 71.97 | Advanced stage, metastatic | Active treatment | |
To assess the adoption, adherence, and user experience of a digital patient monitoring (DPM) tool for lung and breast cancer patients in routine clinical practice | usability measure, cohort study | Digital monitoring tool (Kaiku Health DPM) for symptom reporting and management | healthcare providers | home-based | 15 months | weekly | NA | Adults with advanced lung cancer (NSCLC) or HER2-positive breast cancer | 30–60+ | Advanced stage, metastatic | Pre-treatment | |
Test the Lalaby App for monitoring the quality of life of lung cancer patients | Structured interviews before and after the use of the app’s weekly user experience questionnaire with lung cancer patients | A Lalaby App that requires patients to report activities/symptoms twice a day and complete a questionnaire on QOL weekly | Research team | home-based | 6 weeks | daily/weekly | NA | Two Caucasian male patients diagnosed with stage IV Non-Small Cell Lung Cancer receiving intravenous treatment participated in the study. | 55–75 | Advanced stage, metastatic | Active treatment | |
To evaluate if telehealth-delivered palliative care is as effective as in-person care in maintaining the quality of life in advanced NSCLC patients | A multisite randomized comparative effectiveness trial | Early palliative care via secure video | Physician | home-based | Ongoing throughout disease; primary assessment at 24 weeks | Every 4 weeks, with an initial in-person visit for the telehealth group | NA | Adults with advanced NSCLC, 54% female, primarily White (82.7%) | 58.9–73 | Advanced stage, metastatic | Active treatment | |
To assess the feasibility, acceptability, and efficacy of a virtual integrative oncology shared medical appointment (SMA) for symptom management in cancer patients | Prospective cohort pilot study | 7-session, hour-long series on topics like mindful movement, acupuncture, culinary medicine, and stress management delivered via telehealth | oncologists, acupuncture specialists, yoga therapists, and pastoral care physicians | home-based | 14 weeks | Every two weeks | NA | Mixed cancer types including breast, lymphoma, and lung; 69% female; patients aged 28–93 years, with a median age of 66, 10% lung cancer | 28–93 | NA | Active treatment |