Table 1 Findings of the review

From: Systematic review on the technology’s role in supporting lung cancer patients in the treatment journey

Citation

Objective

Study design

Intervention

Delivery Personnel

Setting

Length

Frequency

Theory

Patient demographics

Age range

Stage

Treatment phase

14

To explore VR as a distraction intervention to relieve symptom distress in adults receiving chemotherapy for breast, colon, and lung cancer

Crossover design where participants served as their control

VR distraction with scenarios including deep sea diving, art museum exploration, ancient worlds, and solving a mystery

Nurses

clinical based

Single session

A single session of VR during one chemotherapy treatment, with a control condition (no VR) for an alternate matched treatment, 45-90 minutes

Lazarus and Folkman’s stress and coping model

Adults with breast, colon, or lung cancer (33%), primarily female (77%), average age of 54, predominantly Caucasian (91%)

32–78

NA

Post-treatment

15

To assess the impact of the cancer care dialogues model (home telehealth program) on age-related differences in health-related quality of life (HRQOL) for cancer patients receiving chemotherapy

Prospective pilot study

Daily telehealth interactions with a care coordinator (registered nurse) to manage chemotherapy-related symptoms

nurses

home-based

6 months

Daily symptom monitoring and weekly follow-up

NA

Veterans with a new cancer diagnosis and planning to undertake chemotherapy, predominantly male

Mean age 63.7 years (10.3)

local and metastatic

Active treatment

16

To develop and evaluate an online resource for stereotactic ablative radiotherapy (SABR) information for lung cancer patients using qualitative user feedback

Qualitative user testing with “think-aloud” and semi-structured interviews

A website designed to provide treatment information for early-stage lung cancer patients considering SABR

oncologists, psychologists

home-based

Single session

One-time user interaction with website

user-centered design principles

Lung cancer patients eligible for SABR, primarily older adults with varied health literacy, NSCLC

Average 64.4 Phase 2, 66.3 Phase 3

local

Active treatment

17

Explore why patients and caregivers use online specialists for cancer questions.

Qualitative study with semi-structured telephone interviews.

Web-based Q&A portal on the DLIC website.

Physician

home-based

NA

Based on needs

NA

lung cancer patients (One patient had small cell lung cancer (SCLC), three had non-small cell lung cancer (NSCLC)

44–62

local and metastatic

Pre-treatment

12

To evaluate the efficacy of an internet-based intervention in improving the quality of life for patients with chronic post-surgical pain (CPSP) after lung cancer surgery

Retrospective cohort study comparing Internet-based intervention with conventional treatment

Internet-based pain management intervention, including remote pain control, lifestyle advice, and psychological support via smartphones and Internet

emergency department hcp

home-based

3 months

Weekly assessments and guidance for the internet-based group

NA

Lung cancer patients with chronic post-surgery pain after thoracotomy or thoracoscopic surgery

average 61 years

NA

Active treatment

18

To assess if a web-mediated follow-up improves overall survival (OS) in advanced-stage lung cancer patients compared to routine follow-up with scheduled CT scans.

Multicenter phase III randomized controlled trial

Web-mediated follow-up using an e-follow-up application for weekly self-scored symptoms, triggering alerts for oncologists based on abnormal results

Physician

home-based

13 months

Weekly symptom reporting via the mobile app; oncologist visits at least every three months for both groups

NA

NSCLC and SCLC

35.7–88.1

local and metastatic

Active treatment

19

To evaluate whether a Web-based symptom self-reporting tool could improve survival by enabling early detection of relapse in lung cancer patients

Retrospective, nonrandomized cohort study with an experimental arm using the “sentinel” Web app for symptom reporting and a control arm with standard follow-up

self-reported symptom assessment via the web application alerts an oncologist for early intervention based on predefined criteria

Physician

home-based

18 months

Weekly

NA

Lung cancer patients with complete response, surgical excision, or detectable but nonprogressive disease

Median age of 63–64 years

local and metastatic

Post-treatment

20

To evaluate the feasibility, usability, and preliminary impact of MyAVL, an interactive patient portal for lung cancer patients

Feasibility study with mixed methods (questionnaires, focus group, log data analysis)

MyAVL portal provides patient education, appointment overview, EMR access, PROs with feedback, and tailored physical activity support

research team

home-based

4 months

Patients accessed MyAVL as often as desired

NA

All white, 47% women, NCSLC patients

40–76

local and metastatic

Active treatment

21

To determine if an automated symptom management system (Symptom Care at Home, SCH) reduces chemotherapy-related symptoms compared to enhanced usual care (UC).

Longitudinal randomized controlled trial

Daily automated symptom reporting, self-management coaching, automated alert for poorly controlled symptoms, and nurse practitioner (NP) follow-up using a decision support system

nurses

home-based

6 months

daily

NA

358 participants, the majority female (75%), White (~80%), and a variety of cancer (lung cancer 17%)

Mean age of 55.77 years

local and metastatic

Active treatment

13

Tests new ways of working to identify unmet needs and support patients’ transition from acute to primary care on completion of treatment.

survey, questionnaire, cohort study

Patients complete eSPARC electronic questionnaires monthly, combined with telephone consultations.

Lung cancer nurse specialists

home-based

6 months

Monthly assessments

NA

20 NSCLC patients’ post-surgery, radiotherapy, or chemotherapy.

50–80+

NA

Active treatment

22

To assess the feasibility and acceptability of tablet-assisted self-reported symptom assessment for lung cancer symptoms

Mixed-method feasibility study

Tablet PC-assisted symptom assessment targeting dyspnea, fatigue, pain, and anxiety

nurses

clinical based

Single session

One-time assessment

NA

newly diagnosed lung cancer patients

53–89

NA

Active treatment

23

Determine the feasibility and efficacy of smartphone app-based PR on exercise capacity, symptom management, and QoL in patients with advanced lung cancer undergoing chemotherapy

prospective, single-arm intervention study

A comprehensive mobile health care app with a pulmonary rehabilitation program and symptom management resources, and an Internet of Things wearable device

Physician

home-based

12 weeks

Daily

NA

46.0% (46/100) were males.

median55.1

local and metastatic

Post-treatment

24

Assess the feasibility of a telehealth physical activity intervention for older adults with cancer and their caregivers.

A pilot study with pre/post assessments of physical and functional outcomes.

Telehealth sessions with PT/OT to improve physical activity before and after surgery.

Physical and occupational therapists

are home-based

5 sessions

Sessions held before surgery post-discharge (days 7, 14, and 2-4 weeks after surgery).

Chronic care self-management model

34 patient/caregiver dyads (16 GI cancer, 18 lung cancer)

68–83

NA

Active treatment

25

Assess the feasibility of HRQoL assessment using ePRO in daily clinical practice.

Single-center prospective feasibility study.

Patients completed HRQoL questionnaires before each visit using tablets or computers.

Physicians, clinical research assistant

both

4 months

before each visit

NA

breast, colorectal, and lung cancer patients receiving systemic therapies. Lung cancer (n = 50)

54–71

local and metastatic

Pre-treatment

26

To assess the impact of telemedicine on time to treatment initiation and accessibility of care for thoracic oncology patients during the COVID-19 pandemic

Retrospective cohort study

Telemedicine visits via phone or video conference

Physician

home-based

3 months

As determined by patient needs and clinical protocol

NA

240 patients with thoracic malignancies, majority NSCLC, SCLC

60–75

local and metastatic

Post-treatment

27

Evaluate Value-Based Healthcare (VBHC) principles with digital weekly follow-up for lung cancer patients.

Mixed method

Digital portal for patient-reported outcome monitoring and follow-up.

oncologists, nurses, dieticians

home-based

30 months

Weekly digital assessments.

Value-Based Healthcare principles.

lung cancer patients (NSCLC and SCLC), 79% male

34–90

local and metastatic

Active treatment

28

To evaluate the feasibility, acceptability, and preliminary effectiveness of a videoconference-based physical activity (PA) program for reducing fatigue in cancer patients on immune checkpoint inhibitors

Single-arm feasibility study

Six-month videoconference-based PA program combining supervised and autonomous sessions targeting fatigue reduction

physiologists

home-based

6 months

Weekly

NA

Of cancer patients experiencing fatigue while on immune checkpoint inhibitors, 18.75% of lung cancer patients

34–72

Advanced stage, metastatic

Post-treatment

29

To investigate the feasibility, acceptability, safety, and potential efficacy of inspiratory muscle training (IMT) and walking promotion to disrupt a postulated “dyspnea-inactivity” spiral.

A parallel group pilot randomized trial

12-week intervention, delivered via telemedicine, consisted of exercise training (IMT + walking), education, and behavior change support.

trainer

home-based

12 weeks

Tele-visits were scheduled for weeks 1, 3, 5, 7, 9, and 12 (bi, tri-weekly)

Social Cognitive Theory

lung cancer survivors from Kaiser Permanente Colorado who completed curative-intent therapy within 1–6 months

Control: 70.3 (7.4), Intervention 68.3(6.4)

local and metastatic

Active treatment

30

To evaluate the efficacy of a mHealth portal, Symptom Care at Home (SCH), in assisting caregivers in managing symptoms for patients in home hospice care.

Randomized controlled trial (RCT)

SCH automated symptom reporting system with caregiver coaching and nurse notifications based on the severity of symptoms

nurses

home-based

Ongoing

daily

NA

Cancer patients in home hospice care, predominantly non-hispanic white, lung cancer 19%

Median 71.97

Advanced stage, metastatic

Active treatment

31

To assess the adoption, adherence, and user experience of a digital patient monitoring (DPM) tool for lung and breast cancer patients in routine clinical practice

usability measure, cohort study

Digital monitoring tool (Kaiku Health DPM) for symptom reporting and management

healthcare providers

home-based

15 months

weekly

NA

Adults with advanced lung cancer (NSCLC) or HER2-positive breast cancer

30–60+

Advanced stage, metastatic

Pre-treatment

32

Test the Lalaby App for monitoring the quality of life of lung cancer patients

Structured interviews before and after the use of the app’s weekly user experience questionnaire with lung cancer patients

A Lalaby App that requires patients to report activities/symptoms twice a day and complete a questionnaire on QOL weekly

Research team

home-based

6 weeks

daily/weekly

NA

Two Caucasian male patients diagnosed with stage IV Non-Small Cell Lung Cancer receiving intravenous treatment participated in the study.

55–75

Advanced stage, metastatic

Active treatment

11

To evaluate if telehealth-delivered palliative care is as effective as in-person care in maintaining the quality of life in advanced NSCLC patients

A multisite randomized comparative effectiveness trial

Early palliative care via secure video

Physician

home-based

Ongoing throughout disease; primary assessment at 24 weeks

Every 4 weeks, with an initial in-person visit for the telehealth group

NA

Adults with advanced NSCLC, 54% female, primarily White (82.7%)

58.9–73

Advanced stage, metastatic

Active treatment

33

To assess the feasibility, acceptability, and efficacy of a virtual integrative oncology shared medical appointment (SMA) for symptom management in cancer patients

Prospective cohort pilot study

7-session, hour-long series on topics like mindful movement, acupuncture, culinary medicine, and stress management delivered via telehealth

oncologists, acupuncture specialists, yoga therapists, and pastoral care physicians

home-based

14 weeks

Every two weeks

NA

Mixed cancer types including breast, lymphoma, and lung; 69% female; patients aged 28–93 years, with a median age of 66, 10% lung cancer

28–93

NA

Active treatment