Fig. 4: Molecular characterization of SSA events triggered by I-AniI at the P5-EGFP transgene. | Communications Biology

Fig. 4: Molecular characterization of SSA events triggered by I-AniI at the P5-EGFP transgene.

From: Transgene removal using an in cis programmed homing endonuclease via single-strand annealing in the mosquito Aedes aegypti

Fig. 4

Predicted end-products resulting from DR-associated DNA repair processes and their rate of occurrence in individuals that lost the P5-EGFP transgene. Blue dotted lines indicate signature sequences that are partially unique to each end-product. ‘Potential 2nd DSBs’ describe additional SSA or NHEJ processes that are predicted to occur on the I-AniI site when it remains intact after the initial DSB repair event.

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