Table 3 Down- and upregulated genes in human LEC following a 24 h-treatment with PEVs

From: Platelet extracellular vesicles preserve lymphatic endothelial cell integrity and enhance lymphatic vessel function

DOWN

UP

Identification

FC

p-value

Identification

FC

p-value

SNORD104

-1.062

1.749

KLB

1.576

1.633

LRRC39

-1.387

1.497

RPS3AP26

1.602

1.692

MX1

-1.491

1.601

AL138828.1

2.055

2.152

RNF213-AS1

-1.499

1.375

VWA7

2.062

1.569

IFIT1

-1.678

3.631

FZD7

3.579

1.623

MX2

-1.727

2.619

ATAD3C

3.646

2.004

IFI44L

-1.779

2.973

 

AC137630.3

-1.809

1.301

MT1E

-1.994

1.423

RSAD2

-2.032

2.502

ATP6V1B1

-2.143

1.458

POU5F2

-2.220

1.444

MT1X

-3.141

1.724

NEURL3

-3.400

1.339

AC016747.4

-3.556

1.500

LCMT1-AS1

-3.590

1.549

PRCD

-3.920

1.321

BX276092.9

-4.027

1.311

AL355377.4

-4.266

1.681

  1. Transcriptomic analysis was performed and genes were either down- and upregulated in PEV-treated LECs compared to control. n = 3 batches of cells treated with PEVs produced from a single donor. FC fold change.
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