Fig. 1: Cd exposure led to a significant shift of cell populations in the cortex of E15.5 mice by scRNA-seq analysis. | Communications Biology

Fig. 1: Cd exposure led to a significant shift of cell populations in the cortex of E15.5 mice by scRNA-seq analysis.

From: A single-cell transcriptomic landscape of cadmium-hindered brain development in mice

Fig. 1

a Schematic of the experimental design and timeline. b The Cd concentration was measured in the embryonic cortex. Data of 4 fetus from 4 pregnant mice in each group are expressed as the mean ± SEM. **p < 0.01, two-tailed Student’s t test. c Combined UMAP plots of cells from control and Cd exposed mice. d UMAP plots of cells by cell population assignment. e Heatmap showing the scaled mean expression of specific marker genes used for cell population determination. f Cell distributions among six determined cell types by percentage in both the control and Cd-exposed groups.

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