Fig. 4: Cd exposure disturbed neuronal subpopulations.
From: A single-cell transcriptomic landscape of cadmium-hindered brain development in mice
a Feature plots revealing the differential distribution of excitatory neurons in control and Cd-exposed mice. b Cell distribution percentages of excitatory neuron clusters in control and Cd-exposed mice. C1, cluster 1; C3, cluster 3; C7, cluster 7; C8, cluster 8. c Cell distribution percentages of interneuron clusters in control and Cd-exposed mice. C2, cluster2; C5, cluster 5. d Venn analysis of excitatory neuron cluster marker genes and DEGs in the four excitatory neuron clusters in control and Cd-exposed groups. e Venn analysis of interneuron cluster marker genes and DEGs in control and Cd-exposed mice. f–h Violin plots showing the expression and distribution of the representative top marker genes in C1, C3, and C8 excitatory neuron clusters. i The mRNA expression of Dcx, Neurod2, Neurod6, and Tubb3 in mouse cortical tissue at different developmental stages. Data of 6 fetus from 6 pregnant mice in each group are expressed as the mean ± SEM. *p < 0.05, two-tailed Student’s t test.
