Fig. 2: PHD2 depletion led to excessive mesendoderm development in mouse embryos. | Communications Biology

Fig. 2: PHD2 depletion led to excessive mesendoderm development in mouse embryos.

From: PHD2 safeguards modest mesendoderm development

Fig. 2

a The schematic diagram showing the mating strategy. b The immunostaining against T and hypoxia probe in PHD2+/+ (n = 3), PHD2+/− (n = 8), and PHD2−/− embryos (n = 4) at the E7.5 stage. c The fluorescence signal spectrum and d positive percentages of T in (b) were measured. Scale bars, 100 μm; A anterior, P posterior, +/+ PHD2+/+, +/− PHD2+/−, −/−, PHD2+/−, ***P < 0.001, ****P < 0.0001, ns not significant.

Back to article page