Fig. 5: Case study of single-cell multiomics from human pancreas islet. | Communications Biology

Fig. 5: Case study of single-cell multiomics from human pancreas islet.

From: DRCTdb: disease-related cell type analysis to decode cell type effect and underlying regulatory mechanisms

Fig. 5

a The bar plot illustrates the relationship between T2D (Type 2 Diabetes) and cell types based on single-cell multiomics data. The dotted line represents the p-value cutoff. b Cell-Cell Communication among T2D related islet cell types, colors represent cell types c GO enrichment of gene which nearby T2D risk SNPs overlapped with beta cell chromatin accessibility (d) GO enrichment of gene which overlapped with T2D risk SNPs. e Gene regulatory network of risk gene in beta cells, cyan represents genes, while each of the other colors represents a transcription factor.

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