Fig. 6: Gene set enrichment analysis (GSEA) of monocyte-derived macrophages in M2G-treated immunocompetent HSE after UVA exposure.
From: Characterization of macrophages associated with human skin models exposed to UV radiation
A Enrichment plot of the “hallmark_oxidative phosphorylation” gene set identified by GSEA that was enriched in the treatment group (HSE.THP1.UV.M2G) compared with the control group (HSE.THP1.UV). The heatmap on the right shows the top 30 ranks of the genes associated with OXPHOS. Signal intensities are illustrated by gradient shades of red (increased) and blue (decreased). B Genes encoding the proteins involved in “UV_response_up” and “Inflammatory response” were downregulated in the treatment group. n = 3 per group.
