Table 1 Several clinically relevant metrics from standalone vLAMPS and coupled vLAMPS-PANIS, critical for the interpretation of the study results, exhibit acceptable to excellent reproducibility

From: A metabolic dysfunction-associated steatotic liver acinus biomimetic induces pancreatic islet dysfunction in a coupled microphysiology system

  1. Reproducibility analysis using the ANOVA p-value for the standalone (n = 10 MPS) and coupled vLAMPS-PANIS (n = 12 MPS) functional metrics collected on day 8. Reproducibility status ranged from Excellent (p-value ≥ 0.1) to Poor (p-value < 0.01). All metrics with a p-value > 0.01 were considered as relevant in the multivariate correlation analysis. A p-value ≥ 0.05 demonstrated a more robust reproducibility across the studies. The status bar shows the classification of reproducibility based on p-values53,54,55. Blank fields were not detectable and/or quantified in the corresponding MPS-platform and/or condition.
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