Fig. 2: FOXP2 overexpression alleviated PE progression in rats. | Communications Biology

Fig. 2: FOXP2 overexpression alleviated PE progression in rats.

From: FOXP2 overexpression upregulates LAMA4 expression and thereby alleviates preeclampsia by regulating trophoblast behavior

Fig. 2

A Urine protein content in urine samples of rats at GD0 and GD19. B SBP and DBP of rats at GD0 and GD19. C IHC analysis for FOXP2 expression. Scale bar = 200 μm (100 ×) or 50 μm (400 ×). D qRT-PCR analysis for the mRNA level of LAMA4. E Western blot analysis for the protein levels of FOXP2 and LAMA4. F Visualization of FOXP2 expression in placental tissues by a microscope. Scale bar = 100 μm. G Placenta, fetus, and uterus appearances of rats. H Weights of placenta and fetus of rats. I Images of H&E-stained placental tissues of rats. Scale bar = 500 μm. Data: mean ± SD. N = 6. *p value < 0.05, **p value < 0.01.

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