Table 1 Activities of silvmeb and pseudomeb against microorganisms and human cells (MIC: μg/mL)
Type | Organism | Strain | Silvmeb | Pseudomeb | Vancomycin | Methicillin |
|---|---|---|---|---|---|---|
Gram-positive bacteria | Bacillus subtilis | ATCC 6633 | 8 | 8 | 1 | <0.125 |
ATCC 23857 | 4 | 8 | 0.25 | <0.125 | ||
JWH | 4 | 4 | 0.25 | <0.125 | ||
Staphylococcus aureus | ATCC 25923 | 8 | 4 | 1 | 8 | |
ATCC 29213 | 4 | 8 | 0.5 | 0.5 | ||
ATCC 6538 | 4 | 4 | 1 | 1 | ||
N315 | 8 | 4 | 1 | 1 | ||
Newman | 4 | 8 | 0.5 | 1 | ||
RN4220 | 4 | 4 | 0.5 | 0.5 | ||
USA300 | 4 | 4 | 1 | 16 | ||
Micrococcus luteus | ATCC 4698 | 4 | 8 | 0.25 | <0.125 | |
Mycobacterium smegmatis | mc2 155 | 32 | 32 | >64 | >64 | |
Enterococcus faecalis | ATCC 51299 | >64 | >64 | 2 | 16 | |
Enterococcus faecium | ATCC 35682 | >64 | >64 | >64 | >64 | |
Streptococcus pyogenes | ATCC 19615 | >64 | >64 | 0.5 | <0.125 | |
Gram-negative bacteria | Escherichia coli | DH5α | >64 | >64 | >64 | >64 |
Acinetobacter baumannii | ATCC 19606 | >64 | >64 | >64 | >64 | |
Klebsiella pneumoniae | ATCC 13883 | >64 | >64 | >64 | >64 | |
Pseudomonas aeruginosa | ATCC 9027 | >64 | >64 | >64 | >64 | |
Fungi | Candida albicans | ATCC 10231 | >64 | >64 | >64 | >64 |
Saccharomyces cerevisiae | BY4741 | >64 | >64 | >64 | >64 | |
Human cell | HeLa | >64 | >64 | >64 | >64 | |
H295R | >64 | >64 | >64 | >64 |
