Fig. 7: LINC02139 reinforces GC cell proliferation and restrains apoptosis by targeting XIAP in vivo.

A The whole body and subcutaneous tumors of the nude mice. B The growth curves of the subcutaneous tumor. ****P < 0.001. C The tumor weight of different groups. ****P < 0.001. D HE staining was performed to verify the subcutaneous tumors. E–J Ki-67, CD105, and Cleaved Caspase 3 expression levels in the subcutaneous tumors were detected using IHC (E, G, I). The proliferation index, microvascular density, and positive percentage of Cleaved Caspase 3 were calculated (F, H, J). ****P < 0.001. Scale bars, 100 μm in (D) and (E, G, I).