Table 1 Lipid signature of Lef-NP

From: Lipid-nanoparticle-induced vacuolization in microglia

Lipid Class

Identified Compounds a

µM

Fatty acids (1)

FA 22:6

1.99

Diacyl glycerols (2)

DG 16:0_18:2

0.316

DG 18:2_18:2

0.233

Triacyl glycerols (190)

TG 16:0_34:1

26.7

TG 16:0_34:2

27.8

TG 18:1_34:1

26.7

Glycerophosphocholines (PC)

Monoacyl PC (6)

LPC 16:0

0.264

LPC 18:2

0.098

LPC 20:4

0.192

Diacyl PC (23)

PC 36:2

1.83

PC 36:4

1.43

PC 38:4

5,08

1-alkyl, 2 acyl PC (23)

PC O-28:1

0.144

PC O-34:3

0.131

PC O-42:1

0.129

Sphingomyelins (7)

SM 41:1

0.068

SM 42:1

0.193

SM 42:2

0.112

Ceramides (8)

Cer d18:1/22:0

0.052

Cer d18:1/23:0

0.084

Cer d18:1/24:1

0.042

Cer d18:1/25:0

0.029

Cer d18:2/24:0

0.030

Cer d18:2/24:1

0.009

Hex-Cer d18:1/24:0

0.026

Hex-Cer d18:2/24:0

0.056

Cholesteryl esters (3)

CE 18:1

0.281

CE 20:4

0.176

CE 22:6

0.043

  1. aThe total number of identified compounds within the lipid class is given in parentheses. The whole list of identified compounds is provided in Supplementary Table l. For ceramides, all eight identified compounds are listed here.