Fig. 2: Clustering and dissemination of hvCRKP.

A Phylogenetic relatedness of the hv-CRKP (n = 21), CR-hvKP (n = 15) and reference strains (hvKP NTUH-2044 and two CRKP, HS11286 and K55397) was illustrated. Patient ID, clustering, ST, K_locus, O_locus, KPC, NDM, rmpA, rmpA2, sample type and collection date were annotated in the outbreak clone. ST sequence type, KPC K. pneumoniae carbapenemases, NDM New Delhi metallo-β-lactamases. B Timeline of outbreaks of two different hvCRKP. The left showed one chain of clonal spreading of ST65-KL2 CR-hvKP and the right showed five chains of clonal dissemination of ST11-KL64 hv-CRKP. Different chains of clonal transmission were identified by collection date of strains, initial inpatient department, bed location and transplantation surgery. The Fig. 2B was created with BioRender.com by us, and its icons derived from BioRender.