Fig. 4: Virulence phenotype and diversity of hv-CRKP and CR-hvKP.

A The survival rates of K56649 (ST11-KL64 hv-CRKP), K22877 (ST65-KL2 CR-hvKP) and K60365 (ST11-KL64 hv-CRKP) in G. mellonella infection model. B, C Murine model infected with K56649, K22877 and K60365 using different dose (2 × 106 and 2 × 107 CFU, respectively). D Mucoviscosity difference between K56649 and K60365. E, F Comparison of relative thickness and uronic acids content of bacteria capsular between K56649 and K60365. Relative thick was calculated by total diameter/bacterial diameter. G Survival rates of K22877, K56649 and K60365 resistance to macrophage phagocytosis. H Survival rates of K56649 and K60365 inside of macrophage. I Comparison of biofilm formation among K22877, K56649, K60365 and control strains.