Fig. 6: Changes in K caused by genetic and chemical alterations.
From: Data-driven discovery of the interplay between genetic and environmental factors in bacterial growth
A Evaluating the changes in K triggered by either genes or chemicals. Base, Gi, Ej, and GEij indicate the K values of the WT at any medium, of any single-gene knockout strain at the same medium, of the WT at any other medium, and of any single-gene knockout strain at any other medium, respectively. ΔGi, ΔEj, and ΔGEij indicate the changes in K of the corresponding pairs. The details are described in “Methods”. B Histograms of the changes in K caused by strains, media, and their combinations. The total number of changes is indicated. C Definition of the directional changes in K. P and N represent positive and negative changes, respectively. NN, PN, and PP indicate the three patterns of the directional changes of ΔGi and ΔEj. D An example of a NN, PN, and PP scatter plot. 2865, 2524, and 7389 combinations of NN, PP, and PN are shown, respectively, while the base is the WT at medium C0003. E Relative frequencies of NN, PN, and PP at each Base. Color variation indicates PP, PN, and NN. F. Distributions of relative frequencies of PP, PN, and NN. The number of all combinations evaluated in PP, PN, and NN is indicated.
