Fig. 5: Visualization of residue importance and conservation and aligned protein families.

a Protein secondary structure with the color-coded importance level of residues in one example (UID: M0HVG5). The color indicates importance, where red represents higher importance, and blue indicates lower importance. b The amino acid’s frequency and the average importance in the thermophilic proteins. c Plot the A0A1I7KCI7 protein residue conservation score and its importance for each position in the aligned protein families (DNA_helicase_UvrDPEP).