Fig. 4: 1 kHz stimulation in the cortex did not suppress population-level calcium dynamics. | Communications Biology

Fig. 4: 1 kHz stimulation in the cortex did not suppress population-level calcium dynamics.

From: Kilohertz electrical stimulation evokes robust cellular responses like conventional frequencies but distinct population dynamics

Fig. 4

a, c The population fluorescence across all neurons (±95% confidence interval) during 40 Hz (darkest shade), 140 Hz (middle shade), and 1 kHz (lightest shade) stimulation in the (a) CA1 (green) and (c) cortex (yellow). b, d Area under the curve (AUC) during stimulation in the (b) CA1 (Wilcoxon signed-rank test, statistical results in Suppl. Table 1), and (d) cortex (Wilcoxon signed-rank test, statistical results in Suppl. Table 1). Violin plots depict the kernel density overlaid with box plots showing the interquartile range (1x, 1.5x). The white lines in the boxes are the median. All tests are two-tailed. n.s., not significant, *p < 0.05, **p < 0.01, ***p < 0.005.

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