Fig. 7: Stimulation-evoked excitatory and inhibitory response profiles were generally insensitive to stimulation frequencies within each brain region.

a–d Population fluorescence traces as shown in Figs. 5e,h,k,n and 6c,f are replotted here but grouped by brain region for (a, b) activated neurons and (b, d) suppressed neurons. Solid lines were the mean, and the shaded areas were 95% confidence interval. e-l Violin plots quantifying the difference between 40 Hz, 140 Hz and 1 kHz for the (e-f, i-j) activated neurons and (g-h, k-l) suppressed neurons. e, f AUC and Time to peak for activated neurons in the CA1 (Kruskal-Wallis, statistical results in Suppl. Table 1). (g, h) (g) AUC and (h) time to peak for suppressed neurons in the CA1 (Kruskal-Wallis, statistical results in Suppl. Table 1). (i, j) (i) AUC and (j) time to peak for activated neurons in the cortex (Kruskal-Wallis, statistical results in Suppl. Table 1). (k, l) (k) AUC and (l) time to peak for suppressed neurons in the cortex (Kruskal-Wallis, statistical results in Suppl. Table 1). Violin plots depict the kernel density overlaid with box plots showing the interquartile range (1x, 1.5x). The white lines in the boxes are the median. All Kruskal-Wallis tests were performed with a Dunn-Sidak multiple comparisons correction. n.s., not significant, *p < 0.05, **p < 0.01, ***p < 0.005.