Fig. 8: hACE2 expression and transcriptomic analysis in human iPSCs-derived lung organoids.

a Log2 normalized hACE2 expression fold change across different cell clusters in transduced lung organoids. b Log2 normalized eGFP expression across different cell clusters in transduced lung organoids. c Comparative transcriptomic analysis of hACE2 gene expression across different cell clusters between naïve and transduced human iPSC-derived lung organoids, presented as fold change in hACE2 gene expression. scRNA-seq was performed on both naïve and transduced lung organoids 7 days post-transduction. d Representative flow cytometry analysis of eGFP expression in control versus LVV-hACE2-transduced lung organoids.