Fig. 6: hsa_circ_0001599 binds to hnRNPA2B1. | Communications Biology

Fig. 6: hsa_circ_0001599 binds to hnRNPA2B1.

From: hsa_circ_0001599 promotes odontogenic differentiation of human dental pulp stem cells by increasing ITGA2 expression and stability

Fig. 6

a Venn diagram of RBPs that bind to hsa_circ_0001599, as predicted using the starBase and RBPmap databases. b Ion chromatograph. c Histogram of quantitative comparison of peptides between sample groups. d The binding site of hsa_circ_0001599 to hnRNPA2B1 was predicted using the catRAPID database. e The RPISeq database was used to predict the binding ability of hsa_circ_0001599 to hnRNPA2B1. f RIP assay results. g CLIP‒qPCR analysis of the enrichment of different regions of hsa_circ_0001599. h The expression of hnRNPA2B1 in hDPSCs. i Efficiency of hnRNPA2B1 overexpression and knockdown in hDPSCs. j, k Effects of hnRNPA2B1 overexpression or knockdown on the expression of odontogenic differentiation-related proteins in hDPSCs. l ALP and ARS staining results. f, h–l All data were presented as the mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001. n = 3 for each group. l Scale bar, 200 μm.

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