Fig. 6: Impact of TREM2 on the biological functions of GC cells. | Communications Biology

Fig. 6: Impact of TREM2 on the biological functions of GC cells.

From: Defining gastric cancer ecology: the crucial roles of TREM2+ macrophages and fibroblasts in tumor microenvironments

Fig. 6

A Flow cytometry analysis to assess the effect of each group on T cell differentiation; B Flow cytometry analysis to evaluate the impact of each group on T cell activation; C RT-qPCR to examine changes in lipid metabolism molecules in different cell groups; D, E Assessment of cell viability and proliferation ability using CCK8 and plate colony experiments; F–H Scratch assays and Transwell assays to measure changes in cell migration and invasion abilities among different groups; I Flow cytometry analysis of apoptotic events in each group, with data on early and late apoptotic cells shown in the respective histograms. Quantitative data are presented as mean ± standard deviation and inter-group comparisons were made using unpaired t-tests. * denotes P < 0.05 for comparison between two groups, ** indicates P < 0.01, *** indicates P < 0.001, and ns represents no statistical difference between the two groups, with * indicating significance. Cell experiments were conducted in triplicate.

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