Fig. 1: Examining ferroptosis-, inflammation- and angiogenesis-related factors levels in maternal placenta and plasma of control and PE patients. | Communications Biology

Fig. 1: Examining ferroptosis-, inflammation- and angiogenesis-related factors levels in maternal placenta and plasma of control and PE patients.

From: Quercetin alleviates endothelial dysfunction in preeclampsia by inhibiting ferroptosis and inflammation through EGFR binding

Fig. 1

A Schematic representation of tissue sources and detection indicators. B–B3 Representative Western blot images of ACSL4, GPX4, and SLC7A11 (B) and bar charts of quantitative analysis of relative expressions of ACSL4 (B1) (n = 15 per group), GPX4 (B2) (n = 14 per group) and SLC7A11 (B3) (n = 15 per group). C–J Detection of MDA concentration (C), GSH concentration (D), GSH-Px activity (E), and Fe2+ concentration (F) and correlation analysis was implemented between mean arterial pressure (MAP) and MDA concentration (G), GSH concentration (H), GSH-Px activity (I) and Fe2+ concentration (J) in the placenta tissues of patients, respectively (n = 34 per group). K–M The levels of IL-6 (K), IL-10 (L), and TNF-α (M) in the plasma of control and PE patients (n = 72 per group). N–O The levels of sFlt-1 (N) and PLGF (O) in the plasma of control and PE patients (n = 72 per group). The error bars in (B1–B3) represent means ± SD, in (C–F, K–O) represent the median and 25–75% quartiles. *P < 0.05; **P < 0.01; ***P < 0.001.

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