Fig. 4: Assessing the endothelial function. | Communications Biology

Fig. 4: Assessing the endothelial function.

From: Quercetin alleviates endothelial dysfunction in preeclampsia by inhibiting ferroptosis and inflammation through EGFR binding

Fig. 4

A–A2 The FITC-dextran assay of HUVEC. Schematic illustration of the FITC-dextran assay (A), a standard curve of FITC (A1), and the bar charts of 1 h FITC-dextran permeability (A2) from the Control, Erastin, and Erastin + QCT groups (n = 4 per group). B, C Representative images of ZO-1 immunofluorescence staining of HUVEC from the aforementioned three groups (B), and the bar charts of ZO-1 mean fluorescent intensity (C) (n = 3 per group). D–D2 Representative images of the scratch experiment of HUVEC (D) and the bar charts showing 24 h (D1) (n = 3 per group) and 48 h (D2) (n = 3 per group) relative wound closure from the aforementioned three groups. Scale bars = 100 μm in (B) and (D). The error bars in the figure represent means ± SD. **P < 0.01; ***P < 0.001.

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