Fig. 7: Analysis of the PE indicators in a rat model of sRUPP, sRUPP + Fer-1, and sRUPP + QCT. | Communications Biology

Fig. 7: Analysis of the PE indicators in a rat model of sRUPP, sRUPP + Fer-1, and sRUPP + QCT.

From: Quercetin alleviates endothelial dysfunction in preeclampsia by inhibiting ferroptosis and inflammation through EGFR binding

Fig. 7

A The schematic illustration that ferroptosis is blocked in a pregnant rat model of sRUPP. B–B2 The systolic and diastolic pressure from Sham, sRUPP, sRUPP + Fer-1 and sRUPP + QCT groups (B), the systolic blood pressure (B1) and the diastolic blood pressure (B2) on GD17.5 (n = 8 in Sham, n = 10 in sRUPP, n = 6 in sRUPP + Fer-1, n = 8 in sRUPP + QCT). C The 24-h proteinuria from the aforementioned four groups (n = 7 in Sham, n = 7 in sRUPP, n = 6 in sRUPP + Fer-1, n = 8 in sRUPP + QCT). D, E Representative images of glomeruli stained with HE and PAS (D) and the open capillary areas from the aforementioned four groups (E) (n = 74 in Sham, n = 52 in sRUPP, n = 24 in sRUPP + Fer-1, n = 51 in sRUPP + QCT). Scale bars = 100 μm in (D). The error bars in (B) represent means ± SD, in (B1–C, E) represent the median and 25–75% quartiles. **P < 0.01; ***P < 0.001.

Back to article page