Fig. 1: Conserved structure of E2 ubiquitin-conjugating enzymes. | Communications Biology

Fig. 1: Conserved structure of E2 ubiquitin-conjugating enzymes.

From: A nanobody that binds to the backside of the ubiquitin conjugating enzyme Ube2G2 differentially affects interactions with its partner E3 Ligases

Fig. 1

Structures of E2 conjugating enzymes involved in ubiquitination are shown with their respective PDB IDs. Ube2G2 is depicted with the conserved E1, E3, backside region, acidic loop, and active site cysteine along with both termini. Note the conserved fold among most of the members of the E2 family. *Indicates the two catalytically inactive E2s.

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