Fig. 6: HDX-MS analysis of DriD(78-327).
From: Allosteric activation mechanism of DriD, a WYL-domain containing transcription regulator
A HDX difference data for truncated DriD. Cartoons on top of each panel show the difference in deuterium calculated between the states in Da. Color scale and peptide/time course arrangement are the same as in Fig. 4. B Deuterium uptake plots from peptides indicated by grey boxes in panel A, [labeled c –i]. C Deuterium difference at the 1 min time point from panel A for selected peptides plotted onto the structure DriD [PDB ID: 8TP8]. DNABD when truncated, is shown as surface in grey and is shown as cartoon green when added in trans. All HDX-MS data used to make the graphs as well as the complete HDX-MS difference data, are found in the Supplementary Data 1.
