Fig. 6: Neuronal responses to visual stimuli across cell classes. | Communications Biology

Fig. 6: Neuronal responses to visual stimuli across cell classes.

From: Functional role of cell classes in monkey prefrontal cortex after learning a working memory task

Fig. 6

A, B Firing dynamics in the pre-training phase for the spatial and feature tasks, respectively. C, D Firing dynamics in the post-training phase for the spatial and feature tasks, respectively. The left panels display the average spike density function (SDF) of each cell class during the interval from −0.5 s to 4 s relative to the onset of the first stimulus. Gray bars indicate stimulus presentation intervals (0–0.5 s and 2–2.5 s). NS1, NS2, BS1, and BS2 classes are represented in blue, red, yellow, and purple, respectively. The right panels represent the first and second stimulus-evoked responses for each cell class. Stimulus-evoked response refers to the increase in firing rate during stimulus presentation. Each box plot shows the median (horizontal line), interquartile range (box), and whiskers extending to 1.5 times the interquartile range. Gray dots represent individual data points for each unit, and larger black dots indicate group means. Statistical significance was assessed using the Kruskal-Wallis test for multiple comparisons (n.s. indicates no significant difference) and the Mann-Whitney U test with FDR adjustment for pairwise comparisons. Dotted, dashed, and solid lines indicate p < 0.05, p < 0.01, and p < 0.005, respectively (Mann-Whitney U test, FDR adjusted).

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