Table 1 Phenotypes with the highest heritability in each data type estimated by the MPCH method (all time-to-event phenotypes are calculated as time or age since birth dates)
Type | Phenotype | \({\widehat{h}}_{kk}^{2}\) | 95% CI |
---|---|---|---|
Continuous | Standing height | 0.748 | (0.743, 0.752) |
Continuous | Lipoprotein A | 0.731 | (0.729, 0.733) |
Continuous | 3mm weak meridian (left) | 0.719 | (0.712, 0.726) |
Continuous | 3mm weak meridian (right) | 0.673 | (0.463, 0.831) |
Continuous | avMSE | 0.580 | (0.513, 0.644) |
Binary | Ever smoked | 0.402 | (0.342, 0.466) |
Binary | Hypertensive disease | 0.357 | (0.315, 0.401) |
Binary | Ever unenthusiastic / disinterested for a whole week | 0.339 | (0.268, 0.419) |
Binary | Disorders of thyroid gland | 0.291 | (0.253, 0.333) |
Binary | Chronic obstructive pulmonary disease, bronchiectasis, asthma | 0.284 | (0.236, 0.336) |
Ordinal | Hair color (natural, before graying) | 0.488 | (0.480, 0.497) |
Ordinal | Skin color | 0.475 | (0.457, 0.493) |
Ordinal | Felt hated by family member as a child | 0.341 | (0.258, 0.435) |
Ordinal | Frequency of unenthusiasm / disinterest in last 2 weeks | 0.274 | (0.164, 0.421) |
Ordinal | 3mm regularity index for irregular astigmatism level (right) | 0.247 | (0.231, 0.263) |
Time-to-event | Age asthma diagnosed | 0.317 | (0.308, 0.326) |
Time-to-event | Date of chronic obstructive pulmonary disease report | 0.265 | (0.249, 0.281) |
Time-to-event | Age diabetes diagnosed | 0.257 | (0.247, 0.267) |
Time-to-event | Date of myocardial infarction | 0.235 | (0.180, 0.301) |
Time-to-event | Date of STEMI | 0.225 | (0.111, 0.403) |