Table 1 Occupying subsites of multiple complex crystal structures

From: The crystal structure of GH57 family amylopullulanase reveals its dual binding pockets sharing the same catalytic dyad

Protein

Subsite

−5

−4

−3

−3'

−2

−2'

−1

−1'

+1

+2

+3'

 

Substrate

           

WT

Acarbose

 

⚪

⚪

 

⚪

 

⚪

    

G5

 

⚪

⚪

 

⚪

 

⚪

    

E256Q

G5

⚪

⚪

⚪

 

⚪

●

⚪

●

●

●

 

G6

⚪

⚪

⚪

●

⚪

●

⚪

●

●

●

●

E256L

G6

⚪

⚪

⚪

 

⚪

●

⚪

●

●

●

 

D352N

G3G3'

  

⚪

 

⚪

 

⚪

 

⚪

⚪

 

G5

⚪

⚪

⚪

 

⚪

 

⚪

    

G6

 

⚪

⚪

 

⚪

 

⚪

 

⚪

⚪

 

G8

⚪

⚪

⚪

 

⚪

 

⚪

 

⚪

⚪

 
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