Fig. 3: RBAP48 regulates genome-wide mRNA expression in OSCC cells. | Communications Biology

Fig. 3: RBAP48 regulates genome-wide mRNA expression in OSCC cells.

From: RBAP48 facilitates the oral squamous cell carcinoma process in an androgen receptor-dependent and independent manners

Fig. 3

A The dotted graph showed the gene pathways enriched in different groups of gene clusters. Red indicates positive regulation of this pathway, and blue indicates negative regulation of this pathway. The size of the dot plot represented the enrichment degree. B-C GESA analysis represented an increased enrichment of these pathways. (B) the significantly enriched pathway state in the non-treated DHT state, and (C) the situation in the DHT treatment. D Volcanic dots represented significantly altered genes with siRBAP48 up-regulated (red) or down-regulated (green) under non-treated DHT conditions (p < 1e-2, FC > 2). E Genes that typically change in enrichment pathways were shown using heatmaps.

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