Fig. 4: Heat challenge results in a non-canonical heat shock response in bats.
From: Heat stress response in the cave nectar bat Eonycteris spelaea differs from that of Mus musculus
A Volcano plot of up- and down- regulated DEG ( >2 FC and 0.05 < FDR) of HS + R conditions in blood, (B) lung and (C) muscle in bat (Es) (Supplementary Data 2). D Filtered GSEA against GOBP pathways that are enriched in bats (Es) with comparative mice (Mm) enrichment of different condition and organs (Supplementary Data 3). E Transcription factor enrichment analysis of DEG set list upregulated or (F) downregulated in for HS + R timepoint in bat (Es) organs, analysis was done using ChEA3 against ENCODE database (Supplementary Data 5). Figures were created with elements from BioRender (2025). https://BioRender.com/0fcvmt1.
