Fig. 3: After cross-fostering, C57 mice maintain categorized SRM for other-strain mice.
A Schematic of the behavioral paradigm for a five-trial experiment to test the SRM of C57LD:KM mice for same-strain mice within the same litter, where the same C57 mouse from the same litter was used for the first four trials, and a different C57 mouse from the same litter was introduced in the fifth trial. B Statistical analysis of interaction times for the five-trial experiment in Figure A. The SRM pattern of C57LD:KM mice for same strain mice within the same litter is group recognition memory (n = 6). C Schematic of the behavioral paradigm for a five-trial experiment to test the SRM of C57LD:KM mice in distinguishing between same-litter and different-litter same-strain mice, where the same C57 mouse from the same litter was used for the first four trials, and a C57 mouse from a different litter was introduced in the fifth trial. D Statistical analysis of interaction times for the five-trial experiment in Figure C. C57LD:KM mice can distinguish between same-litter and different-litter same strain mice (n = 6). E Schematic of the behavioral paradigm for a five-trial experiment to test the social memory of cross-fostered mice for same-litter and different-litter heterospecific KM mice, where the same KM mouse from the same litter was used for the first four trials, and a KM mouse from a different litter was introduced in the fifth trial. F Statistical analysis of interaction times for the five-trial experiment in E. Both C57LD:KM mice and C57BD:C57 mice can distinguish between same-litter and different-litter KM mice (n = 6). Data displayed as mean±S.E.M. *P < 0.05, **P < 0.01, ***P < 0.001. T1: Trial 1, T4: Trial 4, T5: Trial 5.
