Fig. 3: Reclustering analysis revealed high heterogeneity of LAM.

A UMAP embedding showing four LAM subclusters. B Cluster composition for each tissue. C Tissue/condition composition for each LAM cluster. D UMAP cluster split by tissue. E Top ten signature genes for each LAM cluster. F Pseudotime trajectory involving all monocytes and macrophage in UMAP space. G LAM subclusters shown in previous total MoMAC UMAP space.