Fig. 6: OPTN dysfunction and ocular hypertension induced a similar pattern of microglia activation in the retina.
From: OPTN protects retinal ganglion cells and ameliorates neuroinflammation in optic neuropathies
a Representative IF images showing OPTN knockout and the high IOP model induced microglia activation. Scale bar, 50 μm. b Quantification of microglia activation with OPTN knockout and the high IOP model in retina. Data are shown as mean ± s.e.m. with n = 6 biologically independent samples. ***p < 0.001, ns, not significant. Statistical significance among multiple groups was determined using one-way ANOVA followed by Tukey’s multiple comparisons test.
