Fig. 6: Proteomics analysis of testis, sperm and epididymis in Tex38−/− mice.
From: Disruption of TEX38 impairs sperm morphogenesis and the migration of sperm into the oviduct
Protein of adult mouse testis, sperm, and epididymis was extracted for proteomics analysis. A Histogram diagram shows the number of up-regulated and down-regulated differentially expressed proteins in the testis, epididymis, and sperm of Tex38−/− mice. B Top biological process from GO enrichment analysis of DEPs in Tex38−/− sperm, epididymis and testis. C Volcano plot of differentially expressed proteins between Tex38+/+ and Tex38−/− sperm. Red dots represent upregulated proteins, blue dots represent downregulated proteins, and gray dots represent proteins that were not differentially expressed (P < 0.05, |logFC | >1.5). D Protein expressions of ADAM3, CALR3, CLGN, PDILT in Tex38+/+ and Tex38−/− testis, epididymis, and sperm. E Protein expressions of TEX38, ARRDC5, ATPA14, DNAJB13, TEKT4, GK2, SPATA19, SUN5, and CETN1 in Tex38+/+ and Tex38−/− testis, epididymis, and sperm. F, G Quantitation of protein expressions in (D) and (E) (n = 3). Mann-Whitney U test.
