Fig. 3: Performance evaluation of OncoMark using cross-validation and external datasets.

a Bar plots summarize precision, recall, F1 score, accuracy, and balanced accuracy from two independent rounds of five-fold cross-validation. Individual dots represent performance on each fold, and error bars denote standard deviations. b OncoMark’s generalizability is assessed across synthetic data created from five independent external datasets, using the same evaluation metrics, highlighting robust and consistent predictive performance.