Table 3 Summary of replicated cis-pQTLs in TEDDY
Chr | Protein | No. significant pQTLs (FDR < 0.05) | rsid (annotation) | Beta (SE) | p-value |
|---|---|---|---|---|---|
1 | C8A | 27 | rs856928a (C8B: 500B Downstream) | 0.12 (0.04) | 6.35 × 10−3 |
1 | C8B | 2 | rs607268 (C8A: Intron) | 0.12 (0.04) | 5.91 × 10−3 |
rs676705 (C8A: 500B Downstream) | 0.12 (0.04) | 5.91 × 10−3 | |||
6 | CFB | 23 | rs150978802a (LTA: Intron) | −0.45 (0.11) | 3.92 × 10−5 |
6 | C4A | 12 | rs9263822a (PSORS1C3: Intron) | −0.36 (0.13) | 6.64 × 10−3 |
10 | MBL2 | 4 | rs1800450 (MBL2: Missense) | −0.55 (0.19) | 3.89 × 10−3 |
rs1031101 (MBL2: 2KB Upstream) | −0.55 (0.19) | 3.89 × 10−3 | |||
rs11003128 (MBL2: Upstream) | −0.51 (0.19) | 7.09 × 10−3 | |||
rs11003131 (Intergenic) | −0.51 (0.19) | 7.09 × 10−3 |
