Fig. 2: The distribution in main organs and renal accumulation of Ds. | Communications Biology

Fig. 2: The distribution in main organs and renal accumulation of Ds.

From: Therapeutic potential of Desmodium styracifolium polysaccharide in attenuating nano-calcium oxalate induced renal injury and fibrosis

Fig. 2

A Representative ICG intensity of in vivo images at different time points after i.p. injection of ICG-Ds. n = 3. B Enrichment of the Ds in various organs of mice at different time points. n = 3. C Immunofluorescence staining of mouse kidneys at different time points. (Green: CK-18; Red: ICG-Ds); Magnification is ×200, Scale bar = 100 μm. n = 3. D Fluorescence signal of ICG-Ds obtained from normal (NC+Ds) and modeling mice (DC+Ds), respectively, after ICG-Ds was i.p. injected at 4-h time point. n = 3. E Immunofluorescence staining of mouse kidneys at 4-h time point. n = 3. F, G Quantification of ICG fluorescence intensity. Data are mean ± SD, n = 3, one-way ANOVA. Compared with the 1 h group, ** indicates p < 0.01; and ns indicates p > 0.05, with no statistical difference. Compared with the NC+Ds group, *** indicates p < 0.001.

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