Fig. 3: T1-IFN signaling specific differentially expressed genes in global FFA2 KO islets compared to WT.

A Differentially expressed genes upregulated in FFA2 KO islets are related to T1-IFN signaling, including transcriptional factors, negative regulators, and T1-IFN signaling target genes. B The top enriched gene ontology biological process (GO BP) pathways in global FFA2 KO islets using the GSEA method. N = 3 per genotype.