Fig. 6: AAV-dNmCas9/Nmg15 upregulates UBE3A in AS treated mice.
From: AAV-dCas9 vector unsilences paternal Ube3a in neurons by impeding Ube3a-ATS transcription
a, b Representative images of UBE3A and NEUN immunofluorescence following the completion of behavioral testing in the (a) cortex and (b) dorsal hippocampus from WT control, AS control, and AS treated mice injected at postnatal day 1 with AAV-dNmCas9/NmhsaNT27 or Nmg15. Scale bar, 200 µm.
